Organisers estimate that last night's concert to help revive tourism Toronto, post-SARS devastated drew around 500,000 people.
Mick Jagger said: "I think it is the biggest crowd we have ever played for."
Justin Timberlake said: "I feel like a fish out of water in this line-up, but I'm honoured to take part in the good cause."
Jim Belushi, who joined master of ceremonies Dan Aykroyd for a set by their Have Love Will Travel Revue blues band said: "We're bringing this city back. We're celebrating with music and it's one of the most joyous and communal experiences."
Estimates put tourism losses in the hundreds of millions of dollars since the first SARS outbreak in Mar, with added health care costs of about £465m. 42 people died of SARS in Canada.